universidad de santiago de compostela facultad de medicina bioquímica clínica grado en medicina semestre curso universidad de santiago de. PDF | The evolution of the epidemiology of mortality in developing countries requires the use of indicators additional to cause specific mortality. PDF | The aim of the present study was to determine whether glutathione oxidation occurs in chronic obstructive pulmonary disease (COPD).
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Graft-to-recipient weight ratio lower to 0. The low graft-to-recipient weight ratio GRWR in adult-to-adult living donor liver transplantation LDLT is one of the major risk factors affecting graft survival.
The goal of this study was to evaluate whether the lower limit of the GRWR can be safely reduced without portal pressure modulation in right-lobe LDLT. From toconsecutive patients from a single institute underwent LDLT with right-lobe grafts without portal pressure modulation.
Of these, 23 had a GRWR of less than 0. The baseline demographics showed low model for end-stage liver disease score mean Three groups by GRWR demonstrated similar characteristics except recipient body mass index and donor gender. For small-for-size syndrome, there were 3 Simultaneous multi-slice echo planar diffusion weighted imaging of the liver and the pancreas: Optimization of signal-to-noise ratio and acquisition time and application to intravoxel incoherent motion analysis.
Ten healthy volunteers underwent DWI of the upper abdomen at 3T.
The De Ritis Ratio: The Test of Time
Four schemes were evaluated: No SNR improvement was obtained in scheme ii. Image quality scores were stable for AF2 but decreased for AF3.
Acute liver injury induced by weight -loss herbal supplements. We report three cases of patients with acute liver injury induced by weight -loss herbal supplements. One patient took Hydroxycut while the other two took Herbalife supplements. Liver biopsies for all patients demonstrated findings consistent with drug-induced acute liver injury.
To our knowledge, we are the first institute to report acute liver injury from both of these two types of weight -loss herbal supplements together as a case series. The series emphasizes the importance of taking a cautious approach when consuming herbal supplements for the purpose of weight loss. The spleen-to- liver ratios in hepatic diseases. The sensitivity and specificity were tested and the anterior view yielded somewhat better results than the posterior view but the best results were obtained when both projections were used.
Liver volume in thalassaemia major: Serum alanine aminotransferase ALT and ferritin levels were obtained in the thalassaemia major patients. Body weight is the most important single factor for liver -volume changes in thalassaemia major patients, but elevated ALT also has a significant role.
Direct liver volume measurement for chelation dose adjustment may be advantageous in patients with elevated ALT. It has been generally recognized that fatty liver can often be seen in the obese population. This study was conducted in order to evaluate the association between fatty liver and abdominal fat volume. A total of patients who visited our obesity clinic in the recent three years underwent fat CT scans and abdominal US.
Attenuation difference between liver and spleen on CT was considered as a reference standard for the diagnosis of fatty liver. On US, the echogenicity of the liver parenchyma was measured in three different regions of interest ROI close to the adjacent right kidney in the same slice, avoiding vessels, bile duct, and calcification. Similar measurements were performed in the right renal cortex. Fat measurement HER by hepatic ultrasound correlated well with the amount of abdominal fat. In particular, the VF was found to show a stronger association with fatty liver than SF.
Gut permeability is related to body weightfatty liver disease, and insulin resistance in obese individuals undergoing weight reduction.
The De Ritis Ratio: The Test of Time
Obesity and associated metabolic disorders are related cofiente impairments of the intestinal barrier. Man permeability in obese individuals with and without liver steatosis undergoing a weight -reduction program to test whether an effective weight -loss program improves gut barrier function and whether obese patients with or without liver steatosis differ in this function.
We assessed barrier functions by the oral Lac: Man and the fecal zonulin tests. Insulin resistance was assessed by the homeostatic model assessment index HOMAand liver steatosis by sonography and the fatty liver index FLI.
Man ratio and circulating interleukin IL 6 concentration decreased during intervention from 0. Intestinal permeability is increased in obese patients with steatosis compared with obese patients without. The increased permeability fell to within the previously reported normal range after weight reduction. The data suggest that a leaky gut barrier is linked with liver steatosis and could be a new target for future steatosis therapies.
This trial was registered at clinicaltrials. The spleen- liver uptake ratio in liver scan: We analyzed correlation between changes of the Spleen- Liver Ratio in liver scintigram and hemodynamical changes of the liver ritix overall grades of portal hypertension by non-invasive, scintigraphic method.
And the methods for measurement of the Spleen- Liver Ratio were also reviewed. Hepatic scintiangiograms for seconds with MBq of 99mTc-Sn-phytate followed by liver scintigrams were performed in 62 patients group consisted with clinically proven norma and various diffuse hepatocellular diseases.
Hepatic Perfusion indices were calculated from the Time-Activity Curves of hepatic scintiangiograms. Each Spleen- Liver Ratios of maximum, average ritiis total counts within ROIs of the liver and spleen from both anterior and posterior liver scintigrams and their geometrical means were calculated. Among them, the posterior Spleen- Liver Ratio measured by maximum counts will give the best information.
And matching with Hepatic Perfusion index will be another useful index to evaluate characteristics splenic extraction coefficient of a certain coicente for liver scintigram.
Inverse odds ratio-weighted estimation for causal mediation analysis. An important scientific goal of studies in the health and social sciences is increasingly to determine to what extent the total effect of a point exposure is mediated by an intermediate variable on the causal pathway between the exposure and the outcome. A causal framework has recently been proposed for mediation analysis, which gives rise to new definitions, formal identification results and novel estimators of direct and indirect effects.
In the present paper, the author describes a new inverse odds ratio-weighted approach to estimate so-called natural direct and indirect effects. The approach, which uses as a weight the inverse of an estimate of the odds ratio function relating the exposure and the mediator, is universal in that it can be used to decompose total effects in a number of regression models commonly used in practice.
Specifically, the approach may be used for effect decomposition in generalized linear models with a nonlinear link function, and in a number of other commonly used models such as the Cox proportional hazards regression for a survival outcome. The approach is simple and can be implemented in standard software provided a weight can be specified for each observation. An additional advantage of the method is that it easily incorporates multiple mediators of a categorical, discrete or continuous nature.
Diffusion- weighted MRI for uveal melanoma liver metastasis detection. We aimed to assess the sensitivity of diffusion- weighted DW magnetic resonance MR imaging for the detection of pathologically confirmed uveal melanoma liver metastases UMLM. Sensitivity of the combined set was higher than sensitivity in the two other sets R1: One of the causes of the low accuracy produced, because each attribute has the same effect on the classification process, while some less relevant characteristics lead to miss-classification of the class assignment for new data.
In this research, we proposed Attribute Weighting Based K-Nearest Neighbor Using Gain Ratio as a parameter to see the correlation between each attribute in the data and the Gain Ratio also will be used as the basis for weighting each attribute of the dataset. The accuracy of results is compared to the accuracy acquired from the original KNN method using fold Cross-Validation with several datasets from the UCI Machine Learning repository and KEEL-Dataset Repository, such as abalone, glass identification, haberman, hayes-roth and water quality status.
Based on the result of the test, the proposed method was able to increase the classification accuracy of KNN, where the highest difference of accuracy obtained hayes-roth dataset is worth The average result of the accuracy of all dataset increases the accuracy by 5. Birth weight ratio as an alternative to birth weight percentile to express infant weight in research and clinical practice: To compare birth weight ratio and birth weight percentile to express infant weight when assessing pregnancy outcome.
We performed a national cohort study. Birth weight ratio was calculated as the observed birth weight divided by the median birth weight for gestational age.
Diffusion- weighted MRI of the transplanted liver. To assess the value of diffusion- weighted imaging DWI in evaluating parenchymal disorders following orthotopic liver transplantation OLT. This institutional review board-approved, retrospective study measured the hepatic apparent diffusion coefficients ADC in patients following OLT.
Those with vascular complications or within 3 months of OLT were excluded. Liver biopsy specimens [performed with a dw of 17 days after magnetic resonance imaging MRI ] were recorded for the presence and severity of parenchymal disorders, such as acute cellular rejection, and recurrence of fibrosis in all patients, and the recurrence of viral hepatitis in patients with hepatitis C.
liver weight ratio: Topics by
ADC values cocientw not predict any of the individual parenchymal disorders on logistic regression analysis. However, ADC values are not likely to be reliable in differentiating between the various parenchymal disorders. Effect of short-term carbohydrate overfeeding and long-term weight loss on liver fat in overweight humans.
Cross-sectional studies have identified a high intake of simple sugars as an important dietary dde predicting nonalcoholic fatty liver disease NAFLD. We examined whether overfeeding overweight subjects with simple sugars increases liver fat and de novo lipogenesis DNL and whether this is reversible by weight loss.
Before and after overfeeding and after hypocaloric diet, metabolic variables and liver fat measured by proton magnetic resonance spectroscopy were measured. The ratio of palmitate The increase ds liver fat was proportional to that in DNL. Weight loss restores liver fat to normal. These data indicate clciente the human fatty liver avidly accumulates fat during carbohydrate overfeeding and support a role for DNL in the pathogenesis of NAFLD.
This trial was registered at www. Rutis hepatic retention ratio: A useful index for fatty liver quantification. Xenon hepatic retention ratio was developed for quantifying fatty liver. Data were acquired in frame mode in the hepatic region and both lung bases for 5 min after rebreathing 20 mCi of gaseous Xe and for another 5 min during washout. Static [ 99m Tc]sulfur colloid liver cocientw was performed with the patient in the identical position immediately after the ventilation study and data were stored for liver localization.
A hepatic time-activity curve corrected for background activity was generated. The Xe retention ratio was derived by dividing the activity at 3. The data of 16 controls and 20 patients with fatty liver cociehte analyzed. There was a strong positive correlation between the Xe retention ratios and percentage of fat on biopsy as assessed by the amount of the liver tissue occupied by fat globules on H ampersand E stained sections. The Xe hepatic retention ratio is a simple, accurate and clinically useful index of detecting, quantifying and managing fatty infiltration of the liver.